Synergizing vaccinations with therapeutics for measles eradication

Prospects for Measles Eradication

The global eradication of measles is desirable because the disease occurs almost universally, affects large numbers of children, can cause serious complications, and is responsible for about 900 000 deaths a year in developing countries. The feasibility of a measles eradication programme is suggested by the success of smallpox eradication, the availibility of a heat-stable, cheap, and effective...

The Measles Initiative: moving toward measles eradication.

The World Health Assembly should establish a target date for measles eradication based on continued progress toward existing mortality reduction goals. We have a safe, effective, and inexpensive vaccine; a proven elimination strategy; high country demand; and an effective global partnership. Since it was founded in 2001, the Measles Initiative has supported the vaccination of >900 million child...

Horizontal transmission and measles vaccine: implications for neo-pathogenesis, measles control, and measles eradication

Measles Eradication versus Measles Control: An Economic Analysis

Background: Policy makers choosing whether to eradicate or control measles need to know about the costs of eradication and its alternatives. Methods: This project used a dynamic age-tiered measles transmission model for 6 countries (Bangladesh, Brazil, Colombia, Ethiopia, Tajikistan, and Uganda), which was extrapolated to a linear model that was applied globally. Policy options were constant va...

Comparing measles with previous eradication programs: enabling and constraining factors.

BACKGROUND Five major disease eradication initiatives were initiated during the second half of the 20th century. The enabling and constraining factors-political, social, economic, and other-for these previous and current eradication programs can inform decision making regarding a proposed measles eradication initiative. METHODS We reviewed the literature on the yaws, malaria, smallpox, guinea...